Cefoperazone-d5
Based on 1 Customer Validation
Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.
For research use only. We do not sell to patients.
- Purity: 98.58%
- CAS No.: 2410425-70-4
- Formula: C25H22D5N9O8S2
- Molecular Weight:650.70
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
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β-lactam |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2410425-70-4
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Unlabeled Cas 62893-19-0
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Appearance Solid
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Molecular Weight 650.70
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Formula C25H22D5N9O8S2
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Color White to off-white
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SMILES
OC(C1=C(CSC2=NN=NN2C)CS[C@@]([C@@H]3NC([C@@H](C4=CC=C(C=C4)O)NC(N5C(C(N(CC5)C([2H])([2H])C([2H])([2H])[2H])=O)=O)=O)=O)([H])N1C3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (153.68 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. N Matsubara, et al. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Antimicrob Agents Chemother. 1979 Dec;16(6):731-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5368 mL | 7.6840 mL | 15.3681 mL | 38.4202 mL |
| 5 mM | 0.3074 mL | 1.5368 mL | 3.0736 mL | 7.6840 mL | |
| 10 mM | 0.1537 mL | 0.7684 mL | 1.5368 mL | 3.8420 mL | |
| 15 mM | 0.1025 mL | 0.5123 mL | 1.0245 mL | 2.5613 mL | |
| 20 mM | 0.0768 mL | 0.3842 mL | 0.7684 mL | 1.9210 mL | |
| 25 mM | 0.0615 mL | 0.3074 mL | 0.6147 mL | 1.5368 mL | |
| 30 mM | 0.0512 mL | 0.2561 mL | 0.5123 mL | 1.2807 mL | |
| 40 mM | 0.0384 mL | 0.1921 mL | 0.3842 mL | 0.9605 mL | |
| 50 mM | 0.0307 mL | 0.1537 mL | 0.3074 mL | 0.7684 mL | |
| 60 mM | 0.0256 mL | 0.1281 mL | 0.2561 mL | 0.6403 mL | |
| 80 mM | 0.0192 mL | 0.0961 mL | 0.1921 mL | 0.4803 mL | |
| 100 mM | 0.0154 mL | 0.0768 mL | 0.1537 mL | 0.3842 mL |
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