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WIN site inhibitor 1 

Cat. No.: HY-111753
Handling Instructions

WIN site inhibitor 1 is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WIN site inhibitor 1 displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity.

For research use only. We do not sell to patients.

WIN site inhibitor 1 Chemical Structure

WIN site inhibitor 1 Chemical Structure

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Description

WIN site inhibitor 1 is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WIN site inhibitor 1 displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity[1].

IC50 & Target

Kd: 0.1 nM (WIN)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

498.38

Formula

C₂₅H₂₂Cl₂FN₅O

SMILES

ClC1=CC=C(CNC(C2=CC(CN3C(N(C)C=C3)=N)=CC(C4=C(C)N=C(F)C=C4)=C2)=O)C=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
WIN site inhibitor 1
Cat. No.:
HY-111753
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WIN site inhibitor 1

Cat. No.: HY-111753