Ac-RHKK(Ac)-AMC
Based on 1 Customer Validation
Ac-RHKK(Ac)-AMC (Compound S1) is a fluorescent substrate for SITR6, that is based on p53 sequence. Ac-RHKK(Ac)-AMC mimics H3K56 deacetylation site and significantly increases the deacetylation signal with low signal-to-background ratio. Ac-RHKK(Ac)-AMC can be used for ageing and cancers research.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 1193634-36-4
- Formula: C38H56N12O8
- Molecular Weight:808.93
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 1193634-36-4
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Appearance Solid
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Molecular Weight 808.93
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Formula C38H56N12O8
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Color White to off-white
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Sequence
Ac-Arg-His-Lys-Lys(Ac)-AMC
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Sequence Shortening
Ac-RHKK(Ac)-AMC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (123.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2362 mL | 6.1810 mL | 12.3620 mL | 30.9050 mL |
| 5 mM | 0.2472 mL | 1.2362 mL | 2.4724 mL | 6.1810 mL | |
| 10 mM | 0.1236 mL | 0.6181 mL | 1.2362 mL | 3.0905 mL | |
| 15 mM | 0.0824 mL | 0.4121 mL | 0.8241 mL | 2.0603 mL | |
| 20 mM | 0.0618 mL | 0.3091 mL | 0.6181 mL | 1.5453 mL | |
| 25 mM | 0.0494 mL | 0.2472 mL | 0.4945 mL | 1.2362 mL | |
| 30 mM | 0.0412 mL | 0.2060 mL | 0.4121 mL | 1.0302 mL | |
| 40 mM | 0.0309 mL | 0.1545 mL | 0.3091 mL | 0.7726 mL | |
| 50 mM | 0.0247 mL | 0.1236 mL | 0.2472 mL | 0.6181 mL | |
| 60 mM | 0.0206 mL | 0.1030 mL | 0.2060 mL | 0.5151 mL | |
| 80 mM | 0.0155 mL | 0.0773 mL | 0.1545 mL | 0.3863 mL | |
| 100 mM | 0.0124 mL | 0.0618 mL | 0.1236 mL | 0.3091 mL |