AKR1C3-IN-15
AKR1C3-IN-15 (compound 30) is a potent and selective AKR1C3 inhibitor with an IC50 of 5 nM. AKR1C3-IN-15 enhances Sorafenib (HY-10201)-induced ROS generation, promoted apoptosis, and restored sorafenib sensitivity in HCC models both in vitro and in vivo.
For research use only. We do not sell to patients.
- CAS No.: 3059671-44-9
- Formula: C19H16FNO4
- Molecular Weight:341.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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AKR1C3 5 nM (IC50) |
Chemical Information
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CAS No. 3059671-44-9
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Molecular Weight 341.33
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Formula C19H16FNO4
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SMILES
O=C(C1=CC2=C(C=C(C=C2)F)OC1)N(CC3=CC=C(C=C3)C(O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)