3059671-44-9

AKR1C3-IN-15 Chemical Structure
3059671-44-9

Chemical Structure

AKR1C3-IN-15

  • CAS No.: 3059671-44-9
  • Formula:C19H16FNO4
  • Molecular Weight:341.33

InChIKey: OQIUBBLCWUHZFT-UHFFFAOYSA-N

SMILES: O=C(C1=CC2=C(C=C(C=C2)F)OC1)N(CC3=CC=C(C=C3)C(O)=O)C

Biological Activity: AKR1C3-IN-15 (compound 30) is a potent and selective AKR1C3 inhibitor with an IC50 of 5 nM. AKR1C3-IN-15 enhances Sorafenib (HY-10201)-induced ROS generation, promoted apoptosis, and restored sorafenib sensitivity in HCC models both in vitro and in vivo[1].

Cat. No. Product Name Purity Description Pricing
HY-173453 		AKR1C3-IN-15 AKR1C3-IN-15 (compound 30) is a potent and selective AKR1C3 inhibitor with an IC50 of 5 nM. AKR1C3-IN-15 enhances Sorafenib (HY-10201)-induced ROS generation, promoted apoptosis, and restored sorafenib sensitivity in HCC models both in vitro and in vivo.
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