Amodiaquine impurity 1
Based on 1 Customer Validation
Amodiaquine impurity 1 is an impurity of Amodiaquine (HY-B1322A).
For research use only. We do not sell to patients.
- Purity: 98.70%
- CAS No.: 81099-86-7
- Formula: C15H11ClN2O
- Molecular Weight:270.72
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
39.66 μM
Compound: GNF-Pf-1310
|
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
|
[PMID: 18579783] |
| HUVEC | IC50 |
82 μM
Compound: 4
|
Cytotoxicity against HUVEC after 24 hrs by MTT assay
Cytotoxicity against HUVEC after 24 hrs by MTT assay
|
[PMID: 17591441] |
Chemical Information
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CAS No. 81099-86-7
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Appearance Solid
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Molecular Weight 270.72
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Formula C15H11ClN2O
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Color Light yellow to yellow
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SMILES
OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 20 mg/mL (73.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (249 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6939 mL | 18.4693 mL | 36.9385 mL | 92.3463 mL |
| 5 mM | 0.7388 mL | 3.6939 mL | 7.3877 mL | 18.4693 mL | |
| 10 mM | 0.3694 mL | 1.8469 mL | 3.6939 mL | 9.2346 mL | |
| 15 mM | 0.2463 mL | 1.2313 mL | 2.4626 mL | 6.1564 mL | |
| 20 mM | 0.1847 mL | 0.9235 mL | 1.8469 mL | 4.6173 mL | |
| 25 mM | 0.1478 mL | 0.7388 mL | 1.4775 mL | 3.6939 mL | |
| 30 mM | 0.1231 mL | 0.6156 mL | 1.2313 mL | 3.0782 mL | |
| 40 mM | 0.0923 mL | 0.4617 mL | 0.9235 mL | 2.3087 mL | |
| 50 mM | 0.0739 mL | 0.3694 mL | 0.7388 mL | 1.8469 mL | |
| 60 mM | 0.0616 mL | 0.3078 mL | 0.6156 mL | 1.5391 mL |