Anti-Mouse CD20 Antibody (AISB12)
Based on 1 Customer Validation
Anti-Mouse CD20 Antibody (AISB12) is an anti-mouse CD20 IgG2a monoclonal antibody. Anti-Mouse CD20 Antibody (AISB12) can deplete B cells. Anti-Mouse CD20 Antibody (AISB12) can be used for research on immunology.
For research use only. We do not sell to patients.
- Purity: 96.975%
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Rat IgG2a kappa
Mouse
CD20
Anti-Mouse CD20 Antibody (AISB12) (300 μg, i.p., on day 5, 8, 10, 12, 15 and 18) can clear B cells in female C57BL/6 mice bearing B16F10 tumors[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6 mice (6-12 weeks)[1]
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Dosage:250 μg
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Administration:Intraperitoneal injection (i.p.), 1 week before the first virus injection and continued weekly until the termination of the animals
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Result:Exhausted B cells and completely eliminated IgG antibodies, but IgM antibodies still persisted.
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Animal Model:5×104 B16F10 cells injected female C57BL/6 mice (6-8 weeks)[2]
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Dosage:300 μg
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Administration:Intraperitoneal injection (i.p.), on day 5, 8, 10, 12, 15 and 18
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Result:Successfully cleared B cells.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
Flow cytometry; Western blot
Chemical Information
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Appearance Liquid
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Molecular Weight 150 kDa
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Color Colorless to light yellow
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SMILES
[Anti-Mouse CD20 Antibody (AISB12)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (260 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Chen M, et al. Immune profiling of adeno-associated virus response identifies B cell-specific targets that enable vector re-administration in mice. Gene Ther. 2023 May;30(5):429-442. [Content Brief]
[2]. Au KM, et al. Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy. Sci Adv. 2020 Jul 3;6(27):eaba8564. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse CD20 Antibody (AISB12) Related Classifications
HY-P990139 Related Classifications
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