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Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2)

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Based on 1 Customer Validation

Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) is a recombinant chimeric version of the original 10F.9G2 antibody (HY-P99145). The variable domain sequences are identical to the original 10F.9G2 but the constant region sequences have been switched from rat IgG2b to mouse IgG1. Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) contains a D265A mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) can be used for the research of cancer.

For research use only. We do not sell to patients.

  • Purity : 99.32%
  • Molecular Weight:143.882 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2)
  • Experimental Validation Results for Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2)
  • Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) Chemical Structure
    Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) Chemical Structure
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Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Immobilized Mouse PDL1, His Tag can bind Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2). The EC50 for this effect is 91.87 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 MC38 cells with Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) (HY-P990172, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG H&L (HY-P8005) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Mouse IgG1 (D265A) kappa (HY-P99983, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) Chemical Structure
    1/16
  • Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2)
  • Immobilized Mouse PDL1, His Tag can bind Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2). The EC50 for this effect is 91.87 ng/mL.
  • Flow cytometric analysis of 1X106 MC38 cells with Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) (HY-P990172, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG H&L (HY-P8005) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Mouse IgG1 (D265A) kappa (HY-P99983, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).