2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) 

Cat. No.: HY-P99145 Purity: 99.68%
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Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) is an anti-mouse PD-L1/B7-H1 IgG2b antibody inhibitor derived from host rat. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) can be used for the research of cancer, such as colon cancer.

For research use only. We do not sell to patients.

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Customer Review

Based on 15 publication(s) in Google Scholar

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) Featured Recommendations:

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) Related Antibodies

Top Publications Citing Use of Products

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Aug 28;16(1):8054.  [Abstract]

    In vivo NIR-II fluorescence images, ratio plots and the corresponding ratio signal (F1060 nm/F1525 nm) values at the tumor site on day 10 after anti-PD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody, 100 μg in 100 μL PBS; i.p.; every three days for a total of three doses) treatment in tumor-bearing mice.

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Dec 5;16(1):10880.  [Abstract]

    NIR-IIb fluorescence ratiometric imaging and NIR-IIb fluorescence quantification/ratiometric analysis of different groups. In the immunotherapy group, the mice received intraperitoneal injection of anti-PD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody) on alternate days. On day 7, the mice received intravenous injection with Bi-HCy-ErNPs (n = 6).

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Apr;12(15):e2412109.  [Abstract]

    Tumor size, tumor growth curves, and tumor volume of C57BL/6 mice injected subcutaneously with U14 cells (n = 4). The results showed that anti-mouse PD-L1/B7-H1 antibody (αPD-L1, 3 mg/kg; i.p.; twice a week) monotherapy significantly slowed tumor growth, whereas combination therapy with FK866 (20 mg/kg; i.p.; twice a week) and αPD-L1 achieved the strongest tumor suppressive effect.

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jan 28;23(1):48.  [Abstract]

    Fluorescence microscopy observations of aPDL1-DTX/PFP@Lipid binding to Pan02 cells. Red fluorescence indicates NPs labeled with DiI (scale bar = 25 μm). The results showed that the binding of nanoparticles was reduced in the presence of free aPD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody).

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: J Control Release. 2025 Sep 10:385:113998.  [Abstract]

    Photographs of tumors from the same treatment groups and changes in tumor volume during treatment. antiPD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody, 100 μg/mouse; administered every two days for three doses).

    • Biological Activity

    • Purity & Documentation

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    • Customer Review

    Description

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) is an anti-mouse PD-L1/B7-H1 IgG2b antibody inhibitor derived from host rat. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) can be used for the research of cancer, such as colon cancer[1].

    Isotype

    Rat IgG2b kappa
    Recommend Isotype Controls
    Species Reactivity

    Mouse
    IC50 & Target

    PD-L1/B7-H1
    In Vivo

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) (0.8 mg/kg, ip, every 2 days for 3 doses) exhibits antitumor efficacy against primary tumor and metastatic tumor in CT26 xenograft mouse models[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: CT26 xenograft mouse models[1]
    Dosage: 0.8 mg/kg
    Administration: Intraperitoneally injection, every 2 days for 3 doses
    Result: Inhibited the tumor growth, prolonged the mouse survival rate.
    Gene ID

    60533  [NCBI]

    Accession
    Application

    in vivo PD-L1 blockade; in vitro PD-L1 blockade; Immunofluorescence; Immunohistochemistry (frozen
    Conjugated

    Unconjugated
    Reconsititution

    The product can be reconstituted/diluted with sterile PBS or saline.
    Molecular Weight

    150 kDa

    Appearance

    Liquid

    Color

    Colorless to light yellow

    SMILES

    [Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)]
    Shipping

    Shipping with dry ice.
    Formulation

    Please refer to the lot-specific COA for specific buffer information.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Biological Activity
    • Immobilized PD-L1 Protein, Mouse (HEK293, His, HY-P70632) can bind Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2). The EC50 for this effect is 9.78 ng/mL.
    • Flow cytometric analysis of 1X106 MC38 cells with Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) (HY-P99145, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rat IgG H&L (HY-P89199) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Rat IgG2a kappa (HY-P990679, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
    Purity & Documentation

    Purity: 99.68%

    SDS (251 KB)

    COA (232 KB) SDS-PAGE (69 KB) SEC-HPLC (70 KB)

    Inhibitory Antibodies User Guide (603 KB)
    References
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    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)PD-1/PD-L1PD-1/Programmed death-ligand 1PD-L1B7-H1PD-1CancerCT26Inhibitorinhibitorinhibit

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