Acetyl-Histone H4 Antibody (YA926)
(Synonyms: H4K5ac; H4; H4/n; H4F2; H4FN; FO108; HIST2H4)Acetyl-Histone H4 Antibody (YA926) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Acetyl-Histone H4.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:200 |
Product Details
Acetyl-Histone H4 Antibody (YA926) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Acetyl-Histone H4.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 11 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 11 kDa
Entrez Gene: 121504 Human ; 554313 Human ; 8294 Human ; 8359 Human ; 8360 Human ; 8361 Human ; 8362 Human ; 8363 Human ; 8364 Human ; 8365 Human ; 8366 Human ; 8367 Human ; 8368 Human ; 8370 Human ; 100041230 Mouse ; 319155 Mouse ; 319156 Mouse ; 319157 M
SwissProt: P62805 Human ; P62806 Mouse ; P62804 Rat
OMIM: 619758 Human
A synthetic acetylated peptide around K5 of human Histone H4 (NP_0010292491) RG-(acetyl)K-GG.
Endogenous
Affinity Purified
Non-conjugated
Acetylated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Acetyl-Histone H4 core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
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Subcellular Localization
Nucleus; Chromosome
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Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
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SwissProt ID
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Synonyms
H4K5ac; H4; H4/n; H4F2; H4FN; FO108; HIST2H4
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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