ADI1 Antibody (YA8505)

Cat. No.: HY-P88821: Fiche technique User Guide for Antibodies
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ADI1 Antibody (YA8505) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ADI1.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

ADI1 Antibody (YA8505) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ADI1.

Host

Mouse

Clonality

Monoclonal

Masse moléculaire

Predicted band size: 21.3 kDa

Species Reactivity

Human

SwissProt ID

Q9BV57

Immunogen

Full length human recombinant protein of human ADI1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureté	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site (By similarity). Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway (PubMed:15938715). Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity). Also down-regulates cell migration mediated by MMP14 (PubMed:14718544). Necessary for hepatitis C virus replication in an otherwise non-permissive cell line (PubMed:11602742)

Subcellular Localization：Cytoplasm,Nucleus,Cell membrane

Expression：
Tissue_Specificity: Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney

Isoforms & Post-Translational Modification：Q9BV57 has two isomers: Q9BV57-1: 21498 Da (predicted); Q9BV57-2: 20332 Da (predicted).

Subunit：Monomer (By similarity)

Synonyms

APL1; ARD; Fe-ARD; HMFT1638; MTCBP1; mtnD; Ni-ARD; SIPL

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/baf3-cell.html [Content Brief]