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Cat. No.: HY-P87962

Baf180 Antibody (YA7647)

Baf180 Antibody (YA7647) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Baf180.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue	FC FC: Flow Cytometry	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:100-200	1:100-200	1:50-200	1:50-100	1:50-200

Description

Baf180 Antibody (YA7647) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Baf180.

Host Rabbit
Clonality Recombinant
Observed Molecular Weight

Observed band size: 193 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 193 kDa

Immunogen

A synthesized peptide derived from human PB1

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Baf180 is involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation
Subcellular Localization

Nucleus
Expression

Tissue_Specificity: Widely expressed
Isoforms & Post-Translational Modification

Q86U86 has 9 isomers: Q86U86-1: 192948 Da (predicted); Q86U86-2: 187188 Da (predicted); Q86U86-3: 183690 Da (predicted); Q86U86-4: 181085 Da (predicted); Q86U86-5: 182118 Da (predicted); Q86U86-6: 99142 Da (predicted); Q86U86-7: 183885 Da (predicted); Q86U86-8: 189645 Da (predicted); Q86U86-9: 184043 Da (predicted).
Subunit

Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47/SNF5, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PBRM1/BAF180, ARID2/BAF200 and actin
SwissProt ID

Q86U86