C17ORF53 Antibody (YA4367)

Cat. No.: HY-P84670: Data Sheet User Guide for Antibodies
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C17ORF53 Antibody (YA4367) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to C17ORF53.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

C17ORF53 Antibody (YA4367) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to C17ORF53.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 69.8 kDa

Species Reactivity

Human

SwissProt ID

Q8N3J3

Gene ID

78995 [NCBI]

Immunogen

Purified recombinant fragment of human C17ORF53 (AA: 282-527) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50 FC: 1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：DNA-binding protein involved in homologous recombination that acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis

Subcellular Localization：Nucleus; Chromosome

Isoforms & Post-Translational Modification：Q8N3J3 has 4 isomers: Q8N3J3-1: 69771 Da (predicted); Q8N3J3-2: 14269 Da (predicted); Q8N3J3-3: 56181 Da (predicted); Q8N3J3-4: 69643 Da (predicted).

Subunit：Interacts with MCM8; this interaction is necessary for MCM8-MCM9 helicase complex recruitment to DNA damage sites (PubMed:31467087). Interacts with RPA1; this interaction associates HROB with the RPA complex (By similarity)

Documentation

User Guide for Antibodies (1077 KB)