C17ORF53 Antibody (YA4367)
C17ORF53 Antibody (YA4367) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to C17ORF53.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:50 FC: 1:200-1:400 | 1:10000 |
Product Details
C17ORF53 Antibody (YA4367) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to C17ORF53.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 69.8 kDa
Purified recombinant fragment of human C17ORF53 (AA: 282-527) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
C17ORF53 is a DNA-binding protein involved in homologous recombination that acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis
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Subcellular Localization
Nucleus; Chromosome
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Isoforms & Post-Translational Modification
Q8N3J3 has 4 isomers: Q8N3J3-1: 69771 Da (predicted); Q8N3J3-2: 14269 Da (predicted); Q8N3J3-3: 56181 Da (predicted); Q8N3J3-4: 69643 Da (predicted).
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Subunit
Interacts with MCM8; this interaction is necessary for MCM8-MCM9 helicase complex recruitment to DNA damage sites (PubMed:31467087). Interacts with RPA1; this interaction associates HROB with the RPA complex (By similarity)
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SwissProt ID
Documentation
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