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TACI Antibody (YA3511)

(Synonyms: CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B)
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TACI Antibody (YA3511) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACI.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    ICC/IF, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • TACI Antibody (YA3511) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

TACI Antibody (YA3511) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACI.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 32 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 31.8 kDa
Immunogen

Purified recombinant fragment of human CD267 (AA: extra(1-165)) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    TACI receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity

  • Subcellular Localization

    Membrane; Single-pass type III membrane protein

  • Expression


    Tissue_specificity:It is highly expressed in the spleen, thymus, small intestine, and peripheral blood leukocytes. It is expressed in resting B cells and activated T cells, but not in resting T cells.

  • Isoforms & Post-Translational Modification

    O14836 has 3 isomers: O14836-1: 31816 Da (predicted); O14836-2: 26664 Da (predicted); O14836-3: 19865 Da (predicted).

  • Subunit

    Binds TRAF2, TRAF5 and TRAF6. Binds the NH2-terminal domain of CAMLG with its C-terminus

  • SwissProt ID

    O14836

  • Gene ID
    23495 [NCBI]
  • Synonyms

    CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B

TACI Antibody (YA3511) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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