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  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. CD276/B7H3 Antibody (YA4334)(PBS only)

CD276/B7H3 Antibody (YA4334)(PBS only)

製品番号: HY-P84637A
User Guide for Antibodies Technical Support

CD276/B7H3 Antibody (YA4334) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD276/B7H3.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

CD276/B7H3 Antibody (YA4334) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD276/B7H3.
Host

Mouse
分子量
Predicted band size: 57 kDa;
Observed band size: 100 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat, Rabbit, Monkey
SwissProt ID
Gene ID
Immunogen

Purified recombinant fragment of human CD276 aa 30-130.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:500
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:500
FC
FC: Flow Cytometry
1:200-1:400
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
純度 affinity purified. Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling
Subcellular Localization：Membrane; Single-pass type I membrane protein
Expression：
Tissue_specificity:It is ubiquitous but undetectable in peripheral blood lymphocytes or granulocytes. It is weakly expressed in resting monocytes. It is expressed in monocyte-derived dendritic cells. It is expressed in sinus epithelial cells. It is expressed in extravillous trophoblast cells and Hofbauer cells of the placenta in early pregnancy and at term.

Induction:By bacterial lipopolysaccharides (LPS) in monocytes and by ionomycin in T and B-lymphocytes. Up-regulated in cells mediating rejection of human transplants
Isoforms & Post-Translational Modification：Q5ZPR3 has 4 isomers: Q5ZPR3-1: 57235 Da (predicted); Q5ZPR3-2: 33791 Da (predicted); Q5ZPR3-3: 52761 Da (predicted); Q5ZPR3-4: 57165 Da (predicted).
Subunit：Interacts with TREML2 and this interaction enhances T-cell activation
Synonyms
B7H3; B7-H3; 4Ig-B7-H3; CD276
ドキュメンテーション
User Guide for Antibodies (1077 KB)

CD276/B7H3 Antibody (YA4334)(PBS only) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
CD276/B7H3 Antibody (YA4334)(PBS only)
製品番号:
HY-P84637A
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