CD368 Antibody (YA4390)(PBS only)

Cat. No.: HY-P84693A: Data Sheet User Guide for Antibodies
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CD368 Antibody (YA4390) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD368.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CD368 Antibody (YA4390) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD368.

Host

Mouse

Molecular Weight

Predicted band size: 24.7 kDa;

Observed band size: 25-30 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8WXI8

Gene ID

338339 [NCBI]

Immunogen

Purified recombinant fragment of human CD368 (AA: extra 39-215) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：Q16576 has 2 isomers: Q16576-1: 47820 Da (predicted); Q16576-2: 52314 Da (predicted).

Subunit：Binds directly to helix 1 of the histone fold of histone H4, a region that is not accessible when H4 is in chromatin (PubMed:18571423, PubMed:9427644).

Synonyms

CLEC4D; MCL; MPCL; CLEC6; CLEC-6; CLECSF8; Dectin-3

Documentation

User Guide for Antibodies (1077 KB)