CD57 Antibody (YA4547)
(Synonyms: B3GAT1; NK1; HNK1; LEU7; NK-1; GLCATP; GLCUATP)CD57 Antibody (YA4547) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD57.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, FC, ELISA
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Reactivity :
Human, Mouse, Rat, Monkey
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
CD57 Antibody (YA4547) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD57.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat, Monkey
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Observed Molecular WeightObserved band size: 41 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 38 kDa
Purified recombinant fragment of human CD57 (AA: 35-191) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD57 is involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group
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Subcellular Localization
Golgi apparatus membrane; Single-pass type II membrane protein; Secreted; Golgi apparatus membrane; Single-pass type II membrane protein; Endoplasmic reticulum membrane; Secreted
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Expression
Tissue_specificity:Primarily expressed in the brain -
Isoforms & Post-Translational Modification
Q9P2W7 has 2 isomers: Q9P2W7-1: 38256 Da (predicted); Q9P2W7-2: 39738 Da (predicted).
The soluble form derives from the membrane form by proteolytic processing -
Subunit
Homodimer. Interacts with SAR1A
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SwissProt ID
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Synonyms
B3GAT1; NK1; HNK1; LEU7; NK-1; GLCATP; GLCUATP
Documentation
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