CD57 Antibody (YA4548)

Cat. No.: HY-P84851: Data Sheet COA
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User Guide for Antibodies
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CD57 Antibody (YA4548) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD57.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CD57 Antibody (YA4548) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD57.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 38 kDa;

Observed band size: 41 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9P2W7

Gene ID

27087 [NCBI]

Immunogen

Purified recombinant fragment of human CD57 (AA: 28-334) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group

Subcellular Localization：Golgi apparatus membrane; Single-pass type II membrane protein; Secreted; Golgi apparatus membrane; Single-pass type II membrane protein; Endoplasmic reticulum membrane; Secreted

Expression：
Tissue_specificity:Primarily expressed in the brain

Isoforms & Post-Translational Modification：Q9P2W7 has 2 isomers: Q9P2W7-1: 38256 Da (predicted); Q9P2W7-2: 39738 Da (predicted).
The soluble form derives from the membrane form by proteolytic processing

Subunit：Homodimer. Interacts with SAR1A

Synonyms

NK1; CD57; HNK1; LEU7; NK-1; GLCATP; GLCUATP

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)