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Cat. No.: HY-P85093

CD73 Antibody (YA4785)

Name: CD73 Antibody (YA4785)
Brand: MedChemExpress
SKU: HY-P85093
Availability: PreOrder

(Synonyms: NT5E; NT5; NTE; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; CD antigen CD73)

CD73 Antibody (YA4785) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD73.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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Quantity

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	ELISA ELISA: Enzyme Linked Immunosorbent Assay	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:200-1:1000	1:10000	1:50-200

Description

CD73 Antibody (YA4785) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD73.

Immunogen

Purified recombinant fragment of CD73 expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Appearance

Solution
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CD73 (NT5E) is a GPI-anchored extracellular 5'-nucleotidase that regulates immune tolerance, inflammation, and tumor immune escape by converting AMP into the immunosuppressive molecule adenosine. In immunological assays, CD73 serves as a key marker for studying Treg function, the immunosuppressive microenvironment, and tumor immunity.
Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor
Isoforms & Post-Translational Modification

CD73 has 2 isomers: P21589-1: 63368 Da (predicted); P21589-2: 57949 Da (predicted).
Subunit

Homodimer
SwissProt ID

P21589
Gene ID

4907 [NCBI]
Synonyms

NT5E; NT5; NTE; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; CD antigen CD73