Claudin 7 Antibody (YA5688)

Cat. No.: HY-P85996: Data Sheet User Guide for Antibodies
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Claudin 7 Antibody (YA5688) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Claudin 7.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Claudin 7 Antibody (YA5688) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Claudin 7.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 22 kDa;

Observed band size: 22 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O95471

Gene ID

1366 [NCBI]

Immunogen

Synthesized peptide derived from human Claudin 7 AA range: 100-211

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:500-5000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Plays a major role in tight junction-specific obliteration of the intercellular space

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Basolateral cell membrane; Cell junction, tight junction

Expression：
Tissue_specificity:This gene is expressed in the kidneys, lungs, and prostate. Isoform 1 appears to be dominant, except in some normal prostate samples where isoform 2 is predominant. In breast cancer, including ductal carcinoma in situ (DCIS) , lobular carcinoma in situ (LCIS) , and invasive ductal carcinoma (IDC) (protein level) , and in various cancer cell lines, this gene expression is downregulated. Loss of expression is associated with histological grade, primarily occurring in high-grade lesions.

Induction:By androgens

Isoforms & Post-Translational Modification：O95471 has 2 isomers: O95471-1: 22418 Da (predicted); O95471-2: 16837 Da (predicted).
Phosphorylated

Subunit：Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity). The phosphorylated form interacts with EPCAM (PubMed:16054130). Does not interact with CD81 (PubMed:20375010)

Synonyms

CEPTR L2; CEPTRL 2; CEPTRL2; Claudin 1; Claudin 7; Claudin 9; Claudin-7; Claudin1; Claudin7; Claudin9; CLD7_HUMAN; CLDN 7; CLDN-7; CLDN7; Clostridium perfringens enterotoxin receptor like 2; CPETR L2; CPETRL 2; CPETRL2; Hs.84359

각종 서류

User Guide for Antibodies (1077 KB)