CLIC2 Antibody (YA7015)
(Synonyms: Chloride intracellular channel 2 antibody; Chloride intracellular channel protein 2 antibody; CLIC 2b antibody; CLIC2 antibody; CLIC2_HUMAN antibody; CLIC2b antibody; MRXS32 antibody; OTTHUMP00000196471 antibody; XAP 121 antibody; XAP121 antibody)CLIC2 Antibody (YA7015) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLIC2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ICC/IF, IHC-P, FC
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Reactivity :
Human
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Formulation:
Supplied in 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:50-1:100 | 1:100-1:500 | 1:100-1:500 |
Product Details
CLIC2 Antibody (YA7015) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLIC2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 28 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 28 kDa
Recombinant protein within human CLIC2 aa 50-247 / 247.
Endogenous
Protein G affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CLIC2 is an In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity (Probable). Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx[1].
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Subcellular Localization
Cytoplasm,Membrane
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Expression
Tissue_Specificity: Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney -
Isoforms & Post-Translational Modification
O15247: 247 amino acids, molecular weight 28356 Da.
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Subunit
Monomer
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SwissProt ID
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Synonyms
Chloride intracellular channel 2 antibody; Chloride intracellular channel protein 2 antibody; CLIC 2b antibody; CLIC2 antibody; CLIC2_HUMAN antibody; CLIC2b antibody; MRXS32 antibody; OTTHUMP00000196471 antibody; XAP 121 antibody; XAP121 antibody
Documentation
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