COX6A1 Antibody (YA7958)(PBS only)
(Synonyms: CMTRID; COX6A; COX6AL)COX6A1 Antibody (YA7958) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to COX6A1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
COX6A1 Antibody (YA7958) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to COX6A1.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 9.6 kDa
Full length human recombinant protein of human COX6A1 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
COX6A1 component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix
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Subcellular Localization
Mitochondrion inner membrane
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Isoforms & Post-Translational Modification
P12074: 109 amino acids, molecular weight 12155 Da.
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Subunit
Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits
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SwissProt ID
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Synonyms
CMTRID; COX6A; COX6AL
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