CRYM (mu Crystallin) Antibody (YA8170)

Cat. No.: HY-P88486: Fiche technique User Guide for Antibodies
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CRYM (mu Crystallin) Antibody (YA8170) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYM (mu Crystallin).

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description

Description

CRYM (mu Crystallin) Antibody (YA8170) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYM (mu Crystallin).

Host

Mouse

Clonality

Monoclonal

Masse moléculaire

Predicted band size: 33.6 kDa

Species Reactivity

Human, Rat, Mouse

SwissProt ID

Q14894

Immunogen

Full length human recombinant protein of human CRYM produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureté	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Catalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including sulfur-containing cyclic ketimines (PubMed:21332720, PubMed:25931162). Under physiological conditions, it efficiently catalyzes delta(1)-piperideine-2-carboxylate (P2C) and delta(1)-pyrroline-2-carboxylate (Pyr2C) reduction, suggesting a central role in lysine and glutamate metabolism (PubMed:25931162). Additional substrates are delta(2)-thiazoline-2-carboxylate (T2C), 3,4-dehydrothiomorpholine-3-carboxylate (AECK), and (R)-lanthionine ketimine (LK) that is reduced at very low rate compared to other substrates (PubMed:25931162). Also catalyzes the NAD(P)H-dependent reduction of (S)-cystathionine ketimine (CysK) (By similarity)

Subcellular Localization：Cytoplasm

Expression：
Tissue_Specificity: Expressed in neural tissues, muscle and kidney (PubMed:1384048). Expressed in the inner ear (PubMed:12471561)

Isoforms & Post-Translational Modification：Q14894: 314 amino acids, molecular weight 33776 Da.

Subunit：Homodimer (PubMed:17242435)

Synonyms

DFNA40; THBP

Documentation

User Guide for Antibodies (1077 KB)