CRYM (mu Crystallin) Antibody (YA8170)
(Synonyms: DFNA40; THBP)CRYM (mu Crystallin) Antibody (YA8170) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYM (mu Crystallin).
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Rat, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
CRYM (mu Crystallin) Antibody (YA8170) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYM (mu Crystallin).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat, Mouse
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Calculated Molecular Weight Predicted band size: 33.6 kDa
Full length human recombinant protein of human CRYM produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CRYM catalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including sulfur-containing cyclic ketimines. Under physiological conditions, it efficiently catalyzes delta(1)-piperideine-2-carboxylate (P2C) and delta(1)-pyrroline-2-carboxylate (Pyr2C) reduction, suggesting a central role in lysine and glutamate metabolism. Additional substrates are delta(2)-thiazoline-2-carboxylate (T2C), 3,4-dehydrothiomorpholine-3-carboxylate (AECK), and (R)-lanthionine ketimine (LK) that is reduced at very low rate compared to other substrates. Also catalyzes the NAD(P)H-dependent reduction of (S)-cystathionine ketimine (CysK)[1][2].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Expressed in neural tissues, muscle and kidney (PubMed:1384048). Expressed in the inner ear (PubMed:12471561) -
Isoforms & Post-Translational Modification
Q14894: 314 amino acids, molecular weight 33776 Da.
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Subunit
Homodimer (PubMed:17242435)
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SwissProt ID
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Synonyms
DFNA40; THBP
Documentation
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