CRYZL1 Antibody (YA8477)

Cat. No.: HY-P88793: Data Sheet User Guide for Antibodies
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CRYZL1 Antibody (YA8477) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYZL1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CRYZL1 Antibody (YA8477) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYZL1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 38.5 kDa

Species Reactivity

Human, Monkey, Mouse, Rat

SwissProt ID

O95825

Immunogen

Full length human recombinant protein of human CRYZL1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary) (PubMed:37267905, PubMed:37267906). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (PubMed:37267905)

Subcellular Localization：Early endosome

Expression：
Tissue_Specificity: Ubiquitous

Isoforms & Post-Translational Modification：O95825 has two isomers: O95825-1: 38697 Da (predicted); O95825-2: 21928 Da (predicted).

Subunit：Homodimer (PubMed:37267906)

Synonyms

4P11; QOH-1

Documentation

User Guide for Antibodies (1077 KB)