CRYZL1 Antibody (YA8477)
(Synonyms: 4P11; QOH-1)CRYZL1 Antibody (YA8477) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYZL1.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Monkey, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:150-500 | 1:100-250 | 1:100 |
Product Details
CRYZL1 Antibody (YA8477) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYZL1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Monkey, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 38.5 kDa
Full length human recombinant protein of human CRYZL1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CRYZL1 component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction[1][2].
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Subcellular Localization
Early endosome
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Expression
Tissue_Specificity: Ubiquitous -
Isoforms & Post-Translational Modification
O95825 has two isomers: O95825-1: 38697 Da (predicted); O95825-2: 21928 Da (predicted).
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Subunit
Homodimer (PubMed:37267906)
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SwissProt ID
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Synonyms
4P11; QOH-1
Documentation
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