CSDE1 Antibody (YA2828)(PBS only)

Cat. No.: HY-P83083A: Data Sheet User Guide for Antibodies
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CSDE1 Antibody (YA2828) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CSDE1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CSDE1 Antibody (YA2828) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CSDE1.

Host

Rabbit

Molecular Weight

Predicted band size: 89 kDa;

Observed band size: 89 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O75534

Gene ID

7812 [NCBI]

Immunogen

A synthetic peptide of human CSDE1/NRU

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：RNA-binding protein involved in translationally coupled mRNA turnover (PubMed:11051545, PubMed:15314026). Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (PubMed:11051545, PubMed:15314026). Required for efficient formation of stress granules (PubMed:29395067); (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA

Subcellular Localization：Cytoplasm; Cytoplasm, Stress granule; Cytoplasm, P-body

Isoforms & Post-Translational Modification：O75534 has 5 isomers: O75534-1: 88885 Da (predicted); O75534-2: 85747 Da (predicted); O75534-3: 90605 Da (predicted); O75534-4: 93742 Da (predicted); O75534-5: 69459 Da (predicted).

Subunit：Component of a multi subunit autoregulatory ribonucleoprotein complex (ARC), at least composed of IGF2BP1, PABPC1 and CSDE1 (PubMed:16356927). Interacts with STRAP (PubMed:10049359). Part of a complex associated with the FOS mCRD domain and consisting of PABPC1, PAIP1, HNRPD and SYNCRIP (PubMed:11051545). The interaction with PABPC1 is direct and RNA-independent (PubMed:11051545, PubMed:15314026). Interacts with EIF4ENIF1/4E-T (PubMed:27342281, PubMed:32354837)

Research Field

Epigenetics and Nuclear Signaling

Synonyms

UNR; D1S155E

Documentation

User Guide for Antibodies (1077 KB)