DBF4 Antibody (YA9757)
(Synonyms: DBF4, DBF4 Zinc Finger, ZDBF1, DBF4A, ASK, Activator Of S Phase Kinase, DBF4-Type Zinc Finger-Containing Protein 1, Zinc Finger, DBF-Type Containing 1, Protein DBF4 Homolog A, DBF4 Zinc Finger A, Chiffon Homolog A, CHIF, Chiffon Homolog (Drosophila), DBF4 Homolog (S. Cerevisiae), DBF4 Homolog, Chif)DBF4 Antibody (YA9757) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to DBF4.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, FC, ICC/IF
-
Reactivity :
Human
-
Formulation:
Supplied in PBS (pH 7.4) containing 50% glycerol, 0.05% BSA and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
FC
FC: Flow Cytometry
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:200-2000 | 1:100-1000 |
Product Details
DBF4 Antibody (YA9757) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to DBF4.
-
Host Rabbit
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 77 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 77 kDa
A synthesized peptide derived from human DBF4
affinity purified.
Non-conjugated
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4) containing 50% glycerol, 0.05% BSA and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
DBF4 is a Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle
-
Subcellular Localization
Nucleus
-
Expression
Tissue_Specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Induction: Induced in G1 phase at low level, increased during G1-S phase and remain high during S and G2-M phase. -
Isoforms & Post-Translational Modification
DBF4 has 2 isoforms, Q9UBU7-1: amino acid length is 674, molecular weight is 76858 Da (predicted); Q9UBU7-2: amino acid length is 234, molecular weight is 26124 Da (predicted).
Phosphorylation increases its interaction with PSIP1. -
Subunit
Forms a complex with CDC7.
-
SwissProt ID
-
Synonyms
DBF4, DBF4 Zinc Finger, ZDBF1, DBF4A, ASK, Activator Of S Phase Kinase, DBF4-Type Zinc Finger-Containing Protein 1, Zinc Finger, DBF-Type Containing 1, Protein DBF4 Homolog A, DBF4 Zinc Finger A, Chiffon Homolog A, CHIF, Chiffon Homolog (Drosophila), DBF4 Homolog (S. Cerevisiae), DBF4 Homolog, Chif
Documentation
Powered by Bioz
