DLX2 Antibody
(Synonyms: Homeobox protein DLX-2, DLX2)DLX2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to DLX2.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P
-
Reactivity :
Human
-
Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
DLX2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to DLX2.
-
Host Rabbit
-
Clonality Polyclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 34 kDa
Synthetic peptide corresponding to the Central region of human DLX2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
DLX2 acts as a transcriptional activator (By similarity). Activates transcription of CGA/alpha-GSU, via binding to the downstream activin regulatory element (DARE) in the gene promoter (By similarity). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis (By similarity)
-
Subcellular Localization
Nucleus
-
Isoforms & Post-Translational Modification
DLX2 has 2 isoforms, Q07687-1: amino acid length is 328, molecular weight is 34243 Da (predicted); Q07687-2: amino acid length is 217, molecular weight is 23021 Da (predicted).
-
Subunit
Interacts (via homeobox DNA-binding domain) with POU4F2; this interaction enhances retinal ganglion cell (RGC) differentiation
-
SwissProt ID
-
Synonyms
Homeobox protein DLX-2, DLX2
Documentation
Powered by Bioz
