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DTNA (Dystrobrevin alpha) Antibody (YA8141)

(Synonyms: D18S892E; DRP3; DTN; DTN-A; LVNC1)

DTNA (Dystrobrevin alpha) Antibody (YA8141) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DTNA (Dystrobrevin alpha).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    WB, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • DTNA (Dystrobrevin alpha) Antibody (YA8141) Product Image
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-2000 1:100-250 1:100

Product Details

Description

DTNA (Dystrobrevin alpha) Antibody (YA8141) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DTNA (Dystrobrevin alpha).

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 58.7 kDa
Immunogen

Full length human recombinant protein of human DTNA produced in HEK293T cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    DTNA may be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors

  • Subcellular Localization

    Cytoplasm,Synapse,Cell membrane

  • Expression


    Tissue_Specificity: Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle

  • Isoforms & Post-Translational Modification

    Q9Y4J8 has 17 isomers: Q9Y4J8-1: 83901 Da (predicted); Q9Y4J8-2: 77653 Da (predicted); Q9Y4J8-3: 65123 Da (predicted); Q9Y4J8-4: 64720 Da (predicted); Q9Y4J8-5: 58874 Da (predicted); Q9Y4J8-6: 43621 Da (predicted); Q9Y4J8-7: 42394 Da (predicted); Q9Y4J8-8: 22108 Da (predicted); Q9Y4J8-9: 41991 Da (predicted); Q9Y4J8-10: 44169 Da (predicted); Q9Y4J8-11: 50417 Da (predicted). Q9Y4J8-12: 36993 Da (predicted); Q9Y4J8-13: 77250 Da (predicted); Q9Y4J8-14: 78064 Da (predicted); Q9Y4J8-15: 82211 Da (predicted); Q9Y4J8-16: 58472 Da (predicted); Q9Y4J8-17: 86781 Da (predicted).
    Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus

  • Subunit

    Interacts with dystrophin, utrophin and the syntrophins SNTA1, SNTB1, SNTB2, SNTG1 and SNTG2

  • SwissProt ID

    Q9Y4J8

  • Synonyms

    D18S892E; DRP3; DTN; DTN-A; LVNC1

DTNA (Dystrobrevin alpha) Antibody (YA8141) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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