Epoxide Hydrolase 1 Antibody (YA2895)
(Synonyms: CEH; SEH; ABHD20)
Based on 1 Customer Validation
Epoxide Hydrolase 1 Antibody (YA2895) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Epoxide Hydrolase 1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:10-1:100 |
Product Details
Epoxide Hydrolase 1 Antibody (YA2895) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Epoxide Hydrolase 1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 63 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 63 kDa
Entrez Gene: 2052 Human ; 13849 Mouse ; 25315 Rat
SwissProt: P07099 Human ; Q9D379 Mouse ; P07687 Rat
OMIM: 132810 Human
A synthetic peptide of human EPHX2
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Epoxide Hydrolase 1 is a Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators; Bifunctional enzyme. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid. Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates[1][2][3][4][5][6].
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Subcellular Localization
Cytoplasm; Peroxisome
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Expression
Induction:By compounds that cause peroxisome proliferation such as clofibrate, tiadenol and fenofibrate -
Isoforms & Post-Translational Modification
P34913 has 3 isomers: P34913-1: 62616 Da (predicted); P34913-2: 57123 Da (predicted); P34913-3: 55626 Da (predicted).
The N-terminus is blocked;The covalent modification of cysteine by 15-deoxy-Delta12,14-prostaglandin-J2 is autocatalytic and reversible. It may occur as an alternative to other cysteine modifications, such as S-nitrosylation and S-palmitoylation (Probable) -
Subunit
Homodimer
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SwissProt ID
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Synonyms
CEH; SEH; ABHD20
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Research Field
Cell Biology
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