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FCAMR/CD351 Antibody (YA7132)(PBS only)

(Synonyms: CD351, FKSG87, FCAMR, High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor, Fc alpha/mu receptor)

FCAMR/CD351 Antibody (YA7132) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FCAMR/CD351.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • FCAMR/CD351 Antibody (YA7132)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:400 1:10000

Product Details

Description

FCAMR/CD351 Antibody (YA7132) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FCAMR/CD351.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 57.1kDa;
Immunogen

Purified recombinant fragment of human CD351 (AA: extra 221-450) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    FCAMR/CD351 functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM

  • Subcellular Localization

    Cell membrane

  • Expression


    Tissue_Specificity: Expressed by mesangial cells
    Induction: Up-regulated by IFNG/IFN-gamma in mesangial cells

  • Isoforms & Post-Translational Modification

    Q8WWV6 has 5 isomers: Q8WWV6-1: 57144 Da (predicted); Q8WWV6-2: 24861 Da (predicted); Q8WWV6-4: 46749 Da (predicted); Q8WWV6-5: 57788 Da (predicted); Q8WWV6-6: 62178 Da (predicted).
    N-glycosylated

  • Subunit

    Interacts with IGHM; this interaction facilitates the endocytosis of IgM-coated microbes or IgM-antigen immune complexes

  • SwissProt ID

    Q8WWV6

  • Synonyms

    CD351, FKSG87, FCAMR, High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor, Fc alpha/mu receptor

FCAMR/CD351 Antibody (YA7132)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • FCAMR/CD351 Antibody (YA7132)(PBS only) Product Image