Flotillin 2 Antibody (YA9714)
(Synonyms: ECS-1, ECS1, Epidermal surface antigen 1, Epidermal surface antigen, ESA, ESA1, Flot2, FLOT2_HUMAN, Flotillin 2 (epidermal surface antigen 1), Flotillin-2)Flotillin 2 Antibody (YA9714) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Flotillin 2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat, Monkey
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:2000-10000 | 1:100 | 1:500-2000 | 1:1000 |
Product Details
Flotillin 2 Antibody (YA9714) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Flotillin 2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat, Monkey
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Calculated Molecular Weight Predicted band size: 47 kDa;
Recombinant protein of human Flotillin-2 (aa 1-428).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Flotillin 2 may act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function
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Subcellular Localization
Cell membrane; Membrane, caveola; Endosome; Membrane
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Expression
Tissue_Specificity: In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes. -
Isoforms & Post-Translational Modification
Flotillin 2 has an amino acid length of 428, molecular weight is 47064 Da.
ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells. -
Subunit
Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2 (By similarity).
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SwissProt ID
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Synonyms
ECS-1, ECS1, Epidermal surface antigen 1, Epidermal surface antigen, ESA, ESA1, Flot2, FLOT2_HUMAN, Flotillin 2 (epidermal surface antigen 1), Flotillin-2
Documentation
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