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Cat. No.: HY-P87847

FPGS Antibody (YA7532)

FPGS Antibody (YA7532) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to FPGS.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Price

Stock

Quantity

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	FC FC: Flow Cytometry
Dilution Ratio	1:1000-1:5000	1:100-1:500

Description

FPGS Antibody (YA7532) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to FPGS.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 65 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 65 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG,Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

FPGS catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates
Subcellular Localization

Mitochondrion inner membrane,Mitochondrion matrix,Cytoplasm
Isoforms & Post-Translational Modification

Q05932 has four isomers: Q05932-1: 64609 Da (predicted); Q05932-2: 60167 Da (predicted); Q05932-3: 59174 Da (predicted); Q05932-4: 61562 Da (predicted).
Subunit

Monomer
SwissProt ID

Q05932