G-CSF Receptor Antibody (YA3373)
(Synonyms: CD 114 antibody; CD114 antibody; CD114 antigen antibody; Colony stimulating factor 3 receptor (granulocyte) antibody; Colony stimulating factor 3 receptor antibody; CSF 3R antibody; CSF3R antibody; CSF3R_HUMAN antibody; Csfgr antibody; G CSF R antibody; G-CSF receptor antibody; G-CSF-R antibody; GCSFR antibody; Granulocyte colony stimulating factor receptor antibody; Granulocyte colony-stimulating factor receptor antibody; OTTHUMP00000009703 antibody; OTTHUMP00000009704 antibody; OTTHUMP00000009705 antibody)G-CSF Receptor Antibody (YA3373) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to G-CSF Receptor.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
G-CSF Receptor Antibody (YA3373) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to G-CSF Receptor.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 92 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 92 kDa
A synthesized peptide derived from human GCSF Receptor (CD114) aa760-836.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
G-CSF Receptor receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface
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Subcellular Localization
Secreted; Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:One or more isoforms were found in the myeloid leukemia cell line KG-1, the leukemia U-937 cell line, bone marrow cells, placenta, and peripheral blood granulocytes. The isoform GCSFR-2 was present only in leukemia U-937 cells. The isoform GCSFR-3 was highly expressed in the placenta. -
Isoforms & Post-Translational Modification
Q99062 has 4 isomers: Q99062-1: 92156 Da (predicted); Q99062-2: 85120 Da (predicted); Q99062-3: 95114 Da (predicted); Q99062-4: 86609 Da (predicted).
N-glycosylated -
Subunit
Homodimer. The dimeric receptor binds two CSF3 molecules.
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SwissProt ID
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Synonyms
CD 114 antibody; CD114 antibody; CD114 antigen antibody; Colony stimulating factor 3 receptor (granulocyte) antibody; Colony stimulating factor 3 receptor antibody; CSF 3R antibody; CSF3R antibody; CSF3R_HUMAN antibody; Csfgr antibody; G CSF R antibody; G-CSF receptor antibody; G-CSF-R antibody; GCSFR antibody; Granulocyte colony stimulating factor receptor antibody; Granulocyte colony-stimulating factor receptor antibody; OTTHUMP00000009703 antibody; OTTHUMP00000009704 antibody; OTTHUMP00000009705 antibody
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Research Field
Immunology
Documentation