HMGA2 Antibody (YA9694)
(Synonyms: HMGA 2, BABL, High mobility group (nonhistone chromosomal) protein isoform I C, High mobility group (nonhistone chromosomal) protein isoform IC, High Mobility Group AT hook 2, High Mobility Group AT hook protein 2, High mobility group AT-hook protein 2, High mobility group protein HMGI C, High mobility group protein HMGI-C, High mobility group protein HMGIC)HMGA2 Antibody (YA9694) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to HMGA2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IHC-P, FC, IF-Tissue
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:1000 | 1:200-1000 | 1:8000 | 1:1000 |
Product Details
HMGA2 Antibody (YA9694) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to HMGA2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 12 kDa;
Synthetic peptide of Human HMGA2 (aa 70-120).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HMGA2 functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner[1].
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
HMGA2 has 6 isoforms, P52926-1: amino acid length is 109, molecular weight is 11832 Da (predicted); P52926-2: amino acid length is 106, molecular weight is 11456 Da (predicted); P52926-3: amino acid length is 86, molecular weight is 9273 Da (predicted); P52926-4: amino acid length is 92, molecular weight is 10063 Da (predicted); P52926-5: amino acid length is 103, molecular weight is 10845 Da (predicted); P52926-6: amino acid length is 90, molecular weight is 9742 Da (predicted).Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2 (By similarity)
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Subunit
Interacts with E4F1.
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SwissProt ID
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Synonyms
HMGA 2, BABL, High mobility group (nonhistone chromosomal) protein isoform I C, High mobility group (nonhistone chromosomal) protein isoform IC, High Mobility Group AT hook 2, High Mobility Group AT hook protein 2, High mobility group AT-hook protein 2, High mobility group protein HMGI C, High mobility group protein HMGI-C, High mobility group protein HMGIC
Documentation
References
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