Huntingtin Antibody (YA7211)

Cat. No.: HY-P87527: Ficha de datos User Guide for Antibodies
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Huntingtin Antibody (YA7211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Huntingtin.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

Huntingtin Antibody (YA7211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Huntingtin.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size: 347 kDa;

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P42858

Immunogen

A synthesized peptide derived from human Huntingtin

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:100-500
FC FC: Flow Cytometry	1μg/Test

Sensitivity	Endogenous	Pureza	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 0.01M tris buffered saline (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：May play a role in microtubule-mediated transport or vesicle function|Promotes the formation of autophagic vesicles

Subcellular Localization：Cytoplasm,Nucleus,Early endosome,Cytoplasmic vesicle, autophagosome

Expression：
Tissue_Specificity: Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation

Isoforms & Post-Translational Modification：P42858: 3142 amino acids, molecular weight 347603 Da.

Subunit：Interacts with PFN1 (PubMed:18573880)

Documentación

User Guide for Antibodies (1077 KB)