ID3 Antibody (YA7932)(PBS only)

Cat. No.: HY-P88248A: Data Sheet User Guide for Antibodies
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ID3 Antibody (YA7932) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ID3.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ID3 Antibody (YA7932) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ID3.

Host

Mouse

Molecular Weight

Predicted band size: 12.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q02535

Immunogen

Full length human recombinant protein of human ID3 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-250
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain
Induction: By phorbol 12-myristate 13-acetate (PMA)

Isoforms & Post-Translational Modification：Q02535: 119 amino acids, molecular weight 12999 Da.

Subunit：Homodimer, and heterodimer with other HLH proteins

Synonyms

bHLHb25; HEIR-1

Documentation

User Guide for Antibodies (1077 KB)