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IQGAP3 Antibody (YA9122)

(Synonyms: Ras GTPase-activating-like protein IQGAP3, IQGAP3)
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IQGAP3 Antibody (YA9122) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IQGAP3.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, IF-Tissue, IP, ELISA

  • Reactivity :

    human, mouse, rat

  • Formulation:

    Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.

  • Conjugation:
    Non-conjugated
  • IQGAP3 Antibody (YA9122) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
IF-Tissue Info
IF-Tissue: Immunofluorescence-Tissue
IP Info
IP: Immunoprecipitation
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1000 1:50-500 1:50-500 1-2μg per 100-500μg Total protein 1:50-3000

Product Details

Description

IQGAP3 Antibody (YA9122) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IQGAP3.

  • Host Mouse
  • Species Reactivity
    human, mouse, rat
  • Calculated Molecular Weight Predicted band size: 185 kDa
Immunogen

A synthesized peptide derived from human IQGAP3.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at 2-8°C for 1 year, do not freeze.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    IQGAP3 is an IQGAP3 belongs to the GTPase isoleucine-glutamine sequence activator protein (IQGAP) family. IQGAP3 specifically serves an indispensable function in both the advancement of the cell cycle and the preservation of genome stability. Extensive evidence substantiates the involvement of IQGAP3 in the inception and progression of diverse malignant neoplasms, with notable prominence in breast cancer, clear cell renal cell carcinoma, and lung cancer. Furthermore, IQGAP3 significantly participates in assorted tumor-related signaling pathways, including the EGFR/ERK signaling pathway, ERK1/2 signaling pathway, MEK/ERK, and p38 signaling pathways[1].

  • SwissProt ID

    Q86VI3

  • Gene ID
    128239 [NCBI]
  • Synonyms

    Ras GTPase-activating-like protein IQGAP3, IQGAP3

[1]. Gao X, et al. IQGAP3 promotes the progression of glioma as an immune and prognostic marker. Oncol Res. 2024 Mar 20;32(4):659-678. [Content Brief]

IQGAP3 Antibody (YA9122) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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