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Cat. No.: HY-P84848A

KLHL13 Antibody (YA4545)(PBS only)

Name: KLHL13 Antibody (YA4545)(PBS only)
Brand: MedChemExpress
SKU: HY-P84848A
Availability: PreOrder

(Synonyms: BKLHD2; FLJ10262; MGC74791; KLHL13)

KLHL13 Antibody (YA4545) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLHL13.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	FCM	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-1:2000	1:200-1:1000	1:200-1:1000	1:200-1:400	1:10000

Description

KLHL13 Antibody (YA4545) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLHL13.

Host Mouse
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 74 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 74 kDa

Immunogen

Purified recombinant fragment of human KLHL13 aa 325-655.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

KLHL13 is a Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis
Isoforms & Post-Translational Modification

Q9P2N7 has 5 isomers: Q9P2N7-1: 73868 Da (predicted); Q9P2N7-2: 69090 Da (predicted); Q9P2N7-3: 72141 Da (predicted); Q9P2N7-4: 73322 Da (predicted); Q9P2N7-5: 74630 Da (predicted).
Subunit

Component of the BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL9, KLHL13 and RBX1. Interacts with AURKB
SwissProt ID

Q9P2N7
Gene ID

90293 [NCBI]
Synonyms

BKLHD2; FLJ10262; MGC74791; KLHL13