LEMD3 (MAN1) Antibody (YA8144)
(Synonyms: MAN1)LEMD3 (MAN1) Antibody (YA8144) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LEMD3 (MAN1).
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF, FC, IP
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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IP 2-4ug/mg
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|---|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
LEMD3 (MAN1) Antibody (YA8144) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LEMD3 (MAN1).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 100.0 kDa
Full length human recombinant protein of human LEMD3 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LEMD3 is a Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest
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Subcellular Localization
Nucleus inner membrane
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Expression
Tissue_Specificity: Heart, brain, placenta, lung, liver and skeletal muscle -
Isoforms & Post-Translational Modification
Q9Y2U8: 911 amino acids, molecular weight 99997 Da.
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Subunit
Interacts with SMAD1, SMAD2, SMAD3 and SMAD5
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SwissProt ID
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Synonyms
MAN1
Documentation
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