LHX3 Antibody (YA2698)
(Synonyms: CPHD3; LHX3; Lim3; M2 LHX3; mLim-3; mLIM3; P LIM)LHX3 Antibody (YA2698) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LHX3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50 | 1:50-1:100 |
Product Details
LHX3 Antibody (YA2698) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LHX3.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 43 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 43 kDa
Entrez Gene: 8022 Human ; 16871 Mouse ; 170671 Rat
SwissProt: Q9UBR4 Human ; P50481 Mouse ;
OMIM: 221750 Human
A synthesized peptide derived from human LHX3 aa300-350.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LHX3 transcription factor. Recognizes and binds to the consensus sequence motif 5'-AATTAATTA-3' in the regulatory elements of target genes, such as glycoprotein hormones alpha chain CGA and visual system homeobox CHX10, positively modulating transcription; transcription can be co-activated by LDB2. Synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1. Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1[1].
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q9UBR4 has 2 isomers: Q9UBR4-1: 43358 Da (predicted); Q9UBR4-2: 43978 Da (predicted).
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Subunit
Interacts with POU1F1 (PubMed:26612202).
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SwissProt ID
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Synonyms
CPHD3; LHX3; Lim3; M2 LHX3; mLim-3; mLIM3; P LIM
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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