LIG1 Antibody (YA3038)(PBS only)

Cat. No.: HY-P83293A: Data Sheet User Guide for Antibodies
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LIG1 Antibody (YA3038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIG1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

LIG1 Antibody (YA3038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIG1.

Host

Rabbit

Molecular Weight

Predicted band size: 102 kDa;

Observed band size: 102 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

P18858

Gene ID

3978 [NCBI]

Immunogen

A synthetic peptide of human LIG1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：DNA ligase that seals nicks in double-stranded during DNA repair (PubMed:30395541). Also involved in DNA replication and DNA recombination

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：P18858 has 3 isomers: P18858-1: 101736 Da (predicted); P18858-2: 88516 Da (predicted); P18858-3: 98228 Da (predicted).

Subunit：Interacts with PCNA (PubMed:24911150). Interacts with POLB (PubMed:19336415)

Research Field

Epigenetics and Nuclear Signaling

Synonyms

LIG1; DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1

Documentation

User Guide for Antibodies (1077 KB)