LYVE1 Antibody (YA3148)(PBS only)
(Synonyms: CRSBP 1; CRSBP-1; CRSBP1; hyaluronic acid receptor)LYVE1 Antibody (YA3148) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LYVE1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP, FC
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Reactivity :
Mouse
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:1000-1:5000 | 1:20-1:50 | 1:50-1:100 |
Product Details
LYVE1 Antibody (YA3148) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LYVE1.
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Host Rabbit
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Species ReactivityMouse
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Observed Molecular WeightObserved band size: 35-70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 35 kDa
Recombinant protein of mouse LYVE1.
Affinity Chromatography
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LYVE1 is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium[1].
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Subunit
Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN
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SwissProt ID
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Synonyms
CRSBP 1; CRSBP-1; CRSBP1; hyaluronic acid receptor
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Research Field
Cardiovascular
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