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MOG Antibody (YA3277)

(Synonyms: BTN6; BTNL11; MOGIG2; NRCLP7)
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Based on 1 Customer Validation

MOG Antibody (YA3277) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MOG.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF

  • Reactivity :

    Rat

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for MOG Antibody (YA3277)
  • MOG Antibody (YA3277) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:500-1:1000 1:50-1:200

Product Details

Description

MOG Antibody (YA3277) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MOG.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Rat
  • Observed Molecular Weight
    Observed band size: 28 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 28 kDa
Species Reactivity Database

Entrez Gene: 24558 Rat

SwissProt: Q63345 Rat

Immunogen

A synthetic peptide of human Myelin oligodendrocyte glycoprotein

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for MOG Antibody (YA3277)
    Western blot analysis of extracts from Rat brain tissue(lane 2(20μg) and Rat brain tissue(lane 3(40μg) using MOG Antibody (HY-P83532). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody ( 1/1000) and Loading control antibody (Beta Actin, HY-P80993，1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001，1/10,000) was used for 1 hour at room temperature.

Background

  • Function

    MOG mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication; (Microbial infection) Acts as a receptor for rubella virus

  • Subcellular Localization

    Cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes

  • Isoforms & Post-Translational Modification

    Q16653 has 13 isomers: Q16653-1: 28193 Da (predicted); Q16653-2: 23627 Da (predicted); Q16653-3: 25353 Da (predicted); Q16653-4: 14988 Da (predicted); Q16653-5: 28647 Da (predicted); Q16653-6: 24081 Da (predicted); Q16653-7: 25807 Da (predicted); Q16653-8: 23264 Da (predicted); Q16653-9: 23021 Da (predicted); Q16653-10: 19334 Da (predicted); Q16653-11: 23250 Da (predicted); Q16653-12: 12149 Da (predicted); Q16653-13: 33528 Da (predicted).

  • Subunit

    Homodimer (By similarity). May form heterodimers between the different isoforms (By similarity)

  • SwissProt ID

    Q16653

  • Gene ID
    4340 [NCBI]
  • Synonyms

    BTN6; BTNL11; MOGIG2; NRCLP7

  • Research Field

    Neuroscience

MOG Antibody (YA3277) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from Rat brain tissue(lane 2(20μg) and Rat brain tissue(lane 3(40μg) using MOG Antibody (HY-P83532). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody ( 1/1000) and Loading control antibody (Beta Actin, HY-P80993，1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001，1/10,000) was used for 1 hour at room temperature.

  • MOG Antibody (YA3277) Product Image
    1/16
  • Experimental Validation Results for MOG Antibody (YA3277)
  • MOG Antibody (YA3277) Product Image
  • Experimental Validation Results for MOG Antibody (YA3277)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from Rat brain tissue(lane 2(20μg) and Rat brain tissue(lane 3(40μg) using MOG Antibody (HY-P83532). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody ( 1/1000) and Loading control antibody (Beta Actin, HY-P80993，1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001，1/10,000) was used for 1 hour at room temperature.
  • Experimental Validation Results for MOG Antibody (YA3277)
  • MOG Antibody (YA3277) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from Rat brain tissue(lane 2(20μg) and Rat brain tissue(lane 3(40μg) using MOG Antibody (HY-P83532). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody ( 1/1000) and Loading control antibody (Beta Actin, HY-P80993，1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001，1/10,000) was used for 1 hour at room temperature.

  • MOG Antibody (YA3277) Product Image WB