MRGPRX2 Antibody (YA7113)

製品番号: HY-P87425: データシート SDS COA User Guide for Antibodies
FAQs
Technical Support

MRGPRX2 Antibody (YA7113) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MRGPRX2.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
20 μL	$135	在庫あり	Estimated Time of Arrival: December 31
50 μL	$215	在庫あり	Estimated Time of Arrival: December 31
100 μL	$345	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

MRGPRX2 Antibody (YA7113) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MRGPRX2.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 37kDa;

Species Reactivity

Human

SwissProt ID

Q96LB1

Immunogen

Purified recombinant fragment of human MRGPRX2 expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	純度	affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A

Subcellular Localization：Cell membrane

Expression：
Tissue_Specificity: Mainly expressed in mast cells. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion (PubMed:12915402). Detected in blood vessels, scattered lymphocytes, and gastrointestinal ganglia (at protein level) (PubMed:16161007)

Isoforms & Post-Translational Modification：Q96LB1: 330 amino acids, molecular weight 37099 Da.

Database

SwissProt: SwissProt: Q96LB1

ドキュメンテーション

Select Batch:

データシート (230 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

MRGPRX2 Antibody (YA7113) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MRGPRX2 Antibody (YA7113)

Product Detail

Background

説明

MRGPRX2 Antibody (YA7113) 関連分類

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