Musashi 2 Antibody (YA4976)

Cat. No.: HY-P85284: Ficha de datos User Guide for Antibodies
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Musashi 2 Antibody (YA4976) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Musashi 2.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

Musashi 2 Antibody (YA4976) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Musashi 2.

Host

Rabbit

Clonality

Monoclonal,Recombinant

Peso molecular

Predicted band size: 35 kDa;

Observed band size: 35 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q96DH6

Gene ID

124540 [NCBI]

Immunogen

A synthesized peptide derived from human MSI2. The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:100-500
FC FC: Flow Cytometry	1:50-100

Sensitivity	Endogenous	Pureza	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity)

Subcellular Localization：Cytoplasm

Expression：
Tissue_specificity:It is ubiquitous; it can be detected even at low concentrations.

Induction:Up-regulated in astrocytes after brain injury

Isoforms & Post-Translational Modification：Q96DH6 has 3 isomers: Q96DH6-1: 35197 Da (predicted); Q96DH6-2: 28421 Da (predicted); Q96DH6-3: 17238 Da (predicted).
Phosphorylated. Ubiquitinated by the RHOBTB2-CUL3-RBX1 ubiquitin ligase complex (PubMed:27941885)

Subunit：Interacts with RHOBTB2; the interaction is necessary for MSI2 ubiquitination and degradation

Synonyms

MSI2; RNA-binding protein Musashi homolog 2; Musashi-2

Documentación

User Guide for Antibodies (1077 KB)