MTAP Antibody (YA7286)
(Synonyms: MSAP, MTAP, S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAPase)Based on 1 Customer Validation
MTAP Antibody (YA7286) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MTAP.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue, FC, ICC/IF, IP
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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FC
FC: Flow Cytometry
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-200 | 1:100-200 | 1:100-200 | 1:50-100 | 1:50-200 | 1:20-50 |
Product Details
MTAP Antibody (YA7286) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MTAP.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse Predicted Reactivity: RatNote: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 29 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 31 kDa
A synthesized peptide derived from human MTAP: 201-283.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MTAP catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates
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Subcellular Localization
Cytoplasm,Nucleus
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Expression
Tissue_Specificity: Ubiquitously expressed -
Isoforms & Post-Translational Modification
Q13126 has 7 isomers: Q13126-1: 31236 Da (predicted); Q13126-2: 38356 Da (predicted); Q13126-3: 36936 Da (predicted); Q13126-4: 30838 Da (predicted); Q13126-5: 33797 Da (predicted); Q13126-6: 32376 Da (predicted); Q13126-7: 26278 Da (predicted).
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Subunit
Homotrimer
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SwissProt ID
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Synonyms
MSAP, MTAP, S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAPase
Documentation