NAPEPLD (NAPE-PLD) Antibody (YA7783)

Cat. No.: HY-P88099: Data Sheet User Guide for Antibodies
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NAPEPLD (NAPE-PLD) Antibody (YA7783) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NAPEPLD (NAPE-PLD).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈	가격	재고
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

NAPEPLD (NAPE-PLD) Antibody (YA7783) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NAPEPLD (NAPE-PLD).

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 45.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q6IQ20

Immunogen

Full length human recombinant protein of human NAPEPLD produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid (PubMed:14634025, PubMed:16527816, PubMed:25684574, PubMed:27571266). Cleaves the terminal phosphodiester bond of diacyl- and alkenylacyl-NAPEs, primarily playing a role in the generation of long-chain saturated and monounsaturated NAEs in the brain (By similarity). May control NAPE homeostasis in dopaminergic neuron membranes and regulate neuron survival, partly through RAC1 activation (By similarity). As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose. Has limited D-type phospholipase activity toward N-acyl lyso-NAPEs (By similarity)

Subcellular Localization：Golgi apparatus membrane,Early endosome membrane,Nucleus envelope,Nucleus, nucleoplasm

Expression：
Tissue_Specificity: Widely expressed. Highest expression in brain, kidney and testis (at protein level). Expressed in adipose tissue (at protein level)

Isoforms & Post-Translational Modification：Q6IQ20: 393 amino acids, molecular weight 45596 Da.

Subunit：Homodimer

Synonyms

FMP30; NAPE-PLD

각종 서류

User Guide for Antibodies (1077 KB)