NRBP1 (MADM) Antibody (YA8421)
(Synonyms: BCON3; MADM; MUDPNP; NRBP)
Based on 1 Customer Validation
NRBP1 (MADM) Antibody (YA8421) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NRBP1 (MADM).
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB, IHC-P, ICC/IF, FC, IP
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Reactivity :
Human, Monkey, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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IP 2ug/500ul
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|---|---|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-500 | 1:100-250 | 1:100 |
Product Details
NRBP1 (MADM) Antibody (YA8421) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NRBP1 (MADM).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Monkey, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 59.8 kDa
Full-length protein expressed in 293T cell transfected with human NRBP1 expression vector
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NRBP1 is required for embryonic development. Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes. May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication[1][2].
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Subcellular Localization
Cytoplasm, cell cortex,Endomembrane system,Cell projection, lamellipodium
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Expression
Tissue_Specificity: Ubiquitously expressed in all tissues examined with high levels in the testis -
Isoforms & Post-Translational Modification
Q9UHY1: 535 amino acids, molecular weight 59845 Da.
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Subunit
Homodimer (By similarity)
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SwissProt ID
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Synonyms
BCON3; MADM; MUDPNP; NRBP
Documentation
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