NSD3 Antibody (YA9727)
(Synonyms: DKFZp667H044, FLJ20353, Histone lysine N methyltransferase NSD3, Histone-lysine N-methyltransferase NSD3, MGC126766, MGC142029, NSD 3, NSD3_HUMAN, Nuclear set domain containing 3, Nuclear SET domain containing protein 3)NSD3 Antibody (YA9727) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to NSD3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:10000 | 1:50-400 | 1:50-100 |
Product Details
NSD3 Antibody (YA9727) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to NSD3.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 162 kDa;
Synthetic peptide of Human NSD3 (aa 1-50).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NSD3 is a Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression
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Subcellular Localization
Nucleus; Chromosome
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Expression
Tissue_Specificity: Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. -
Isoforms & Post-Translational Modification
NSD3 has 5 isoforms, Q9BZ95-1: amino acid length is 1437, molecular weight is 161613 Da (predicted); Q9BZ95-2: amino acid length is 1388, molecular weight is 156070 Da (predicted); Q9BZ95-3: amino acid length is 645, molecular weight is 72621 Da (predicted); Q9BZ95-4: amino acid length is 1374, molecular weight is 154519 Da (predicted); Q9BZ95-5: amino acid length is 1426, molecular weight is 160314 Da (predicted).NSD3 存在 5 个异构体，Q9BZ95-1：氨基酸个数为 1437 个，分子量为 161613 Da (预测)；Q9BZ95-2：氨基酸个数为 1388 个，分子量为 156070 Da (预测)；Q9BZ95-3：氨基酸个数为 645 个，分子量为 72621 Da (预测)；Q9BZ95-4：氨基酸个数为 1374 个，分子量为 154519 Da (预测)；Q9BZ95-5：氨基酸个数为 1426 个，分子量为 160314 Da (预测)。
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Subunit
Interacts with BRD4.
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SwissProt ID
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Synonyms
DKFZp667H044, FLJ20353, Histone lysine N methyltransferase NSD3, Histone-lysine N-methyltransferase NSD3, MGC126766, MGC142029, NSD 3, NSD3_HUMAN, Nuclear set domain containing 3, Nuclear SET domain containing protein 3
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