NSE Antibody (YA1005)(PBS only)

Cat. No.: HY-P81290AA: Data Sheet User Guide for Antibodies
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NSE Antibody (YA1005) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NSE.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

NSE Antibody (YA1005) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NSE.

Host

Mouse

Molecular Weight

Predicted band size: 47 kDa;

Observed band size: 47 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P09104

Gene ID

2026 [NCBI]

Immunogen

Synthetic peptide derived from human NSE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity)

Subcellular Localization：Cytoplasm; Cell membrane

Expression：
Tissue_specificity:α/α homodimers are expressed in embryos and most adult tissues. α/β heterodimers and β/β homodimers are present in skeletal muscle, while α/γ heterodimers and γ/γ homodimers are present in neurons.

Induction:Levels of ENO2 increase dramatically in cardiovascular accidents, cerebral trauma, brain tumors and Creutzfeldt-Jakob disease; (Microbial infection) Activated by human cytomegalovirus (HCMV) UL38 in order to provide the virus with glycosyl building blocks

Isoforms & Post-Translational Modification：P09104 has 2 isomers: P09104-1: 47269 Da (predicted); P09104-2: 42707 Da (predicted).

Subunit：Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific

Research Field

Signal Transduction

Synonyms

ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE

Documentation

User Guide for Antibodies (1077 KB)