NSE Antibody (YA1005)(PBS only)
(Synonyms: ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE)NSE Antibody (YA1005) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NSE.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:10000 |
Product Details
NSE Antibody (YA1005) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NSE.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 47 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 47 kDa
Synthetic peptide derived from human NSE.
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NSE is a Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival
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Subcellular Localization
Cytoplasm; Cell membrane
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Expression
Tissue_specificity:α/α homodimers are expressed in embryos and most adult tissues. α/β heterodimers and β/β homodimers are present in skeletal muscle, while α/γ heterodimers and γ/γ homodimers are present in neurons.
Induction:Levels of ENO2 increase dramatically in cardiovascular accidents, cerebral trauma, brain tumors and Creutzfeldt-Jakob disease; (Microbial infection) Activated by human cytomegalovirus (HCMV) UL38 in order to provide the virus with glycosyl building blocks -
Isoforms & Post-Translational Modification
P09104 has 2 isomers: P09104-1: 47269 Da (predicted); P09104-2: 42707 Da (predicted).
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Subunit
Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific
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SwissProt ID
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Synonyms
ENO2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE
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Research Field
Signal Transduction
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